Mitchell Syndrome Research Proceeds at WashU with New Case Report

In order to know how to best treat Mitchell Syndrome, we still need to learn more about how it works. Dr. Zita Hubler, MD, PhD, is on the case. Dr. Hubler is a postdoc in the lab of Robert Bucelli, MD, PhD, and works in The Miller Lab in Washington University’s Department of Neurology. She and her colleagues conducted the first postmorten neuropathology evaluation of Mitchell Syndrome. This case report, based on her research and appearing in Free Neuropathology, shows how this ultra-rare disease affects neurons and creates some of the neurological symptoms that patients with Mitchell Syndrome display. We are grateful for Dr. Hubler (and her colleagues’) ongoing committment to understanding this disease, and also grateful to the Mitchell Syndrome patients who, after their death, donated their bodies to science so that research like this could take place. The research will be helpful as scientists evaluate possible treatments.

To read the Case Report, click here: https://pmc.ncbi.nlm.nih.gov/articles/PMC12519239/.